Im guessing skype might be leaving some directx hooks open ..Does the problem go away if you shutdown Skype completely?
Dunno why but im thinking of something similar to a file lock issue but with directx hooks... you know IE actually is notorious for leaving a file locked if it *touches* it (upload in IE, etc)
If it doesnt go away with Skype shutdown, Skypes gotta clean up their code and release the calls to Direct X... Sloppy programming
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